At Mercola.com, Dr. Joseph Mercola discusses Akkermansia muciniphila, a gut microbe that might stimulate GLP-1 production naturally. He writes:

• Akkermansia muciniphila is a gut microbe that thrives in your intestinal mucus layer. It’s linked to improved metabolic health, but its levels decrease with age and poor diet
• Studies suggest Akkermansia may support a healthy weight by influencing fat mass, insulin sensitivity, and inflammatory markers, as shown in animal models. It also has roles in glucose and lipid metabolism
• Akkermansia may stimulate natural GLP-1 production. It may also help support blood sugar regulation and cardiovascular health markers
• Research has also linked Akkermansia levels to intestinal barrier integrity, immune regulation, and the gut microbial ecosystem, and has been observed as a marker associated with favorable metabolic profiles
• To boost Akkermansia levels, consume polyphenol-rich foods and high-inulin vegetables. Supplements are available but require careful dosing and timing for effectiveness

Read more here.